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Charles Drew may refer to:
- Charles R. Drew (1904–1950), American physician, surgeon, and medical researcher
- Charles Drew (surgeon) (1916–1987), cardiothoracic surgeon
- Charles S. Drew (1825–1886), representative in the legislature of the Oregon Territory of the United States
- USNS Charles Drew (T-AKE-10), a 2010 Lewis and Clark-class dry cargo ship of the United States Navy
| disambiguation page lists articles associated with the title Charles Drew.
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