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Chemoradiotherapy (CRT, CRTx) is the combination of chemotherapy and radiotherapy to treat cancer.[1] Synonyms include radiochemotherapy (RCTx, RT-CT) and chemoradiation.

Chemoradiation can be concurrent[2] (together) or sequential (one after the other).[3]

The chemotherapy component can be or include a radiosensitizing agent.[2]

Chemoradiotherapy as neoadjuvant therapy before surgery has been shown to be effective in various cancers.[clarification needed][citation needed]


  1. ^ Medical Definition of Chemoradiotherapy
  2. ^ a b Neuner G, Patel A, Suntharalingam M. "Chemoradiotherapy for esophageal cancer". Gastrointest Cancer Res. 3: 57–65. PMC 2684724. PMID 19461907.
  3. ^ Older Patients with GI Cancers Don't Always Receive Tx

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