The uppermost reaches of the Chepo is alternately called the Bayano River after the construction of the Bayano Dam that resulted in the 350-square-kilometre (140 sq mi) lake reservoir. The headwaters of the Chepo encompass watercourses running south from the San Blas Mountains near the Caribbean along with other rivers draining parts of the Majé and Darien Mountains.
The Mamoni River is a major tributary farther down stream.
Measuring 206 kilometres (128 mi) in length, the Chepo-Bayano is the third longest river of Panama.
Coquira, in the lower reaches, is the main riverine port.
- Rand McNally, The New International Atlas, 1993.
- CIA map, 1995.
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