Mastic has been harvested for at least 2,500 years since Greek Antiquity. The first mention of actual mastic 'tears' was by Hippocrates. Hippocrates used mastic for the prevention of digestive problems, colds and as a breath freshener. Roman emperors used mastic along with honey, pepper, and egg in the spiced wine conditum paradoxum. Digestive liqueurs, similar to Mastiha but made with grapes, were known as the Greek elixirs before the French Revolution.