Chlorophenoxy herbicide

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Chlorophenoxy herbicides are a class of herbicide which includes: MCPA, 2,4-D, 2,4,5-T and mecoprop.[1] Large amounts have been produced since the 1950s for agriculture.[2] Acute toxic effects after oral consumption are varied and may include: vomiting, abdominal pain, diarrhoea, gastrointestinal haemorrhage acutely followed by coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations and convulsions.[3] Treatment with urinary alkalinization may be helpful but evidence to support this practice is limited.[1][3]

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  1. ^ a b Roberts DM, Buckley NA (2007). "Urinary alkalinisation for acute chlorophenoxy herbicide poisoning". Cochrane Database Syst Rev (1): CD005488. doi:10.1002/14651858.CD005488.pub2. PMID 17253558.
  2. ^ "Occupational Exposures to Chlorophenoxy Herbicides (IARC Summary & Evaluation, Volume 41, 1986)".
  3. ^ a b Bradberry SM, Proudfoot AT, Vale JA (2004). "Poisoning due to chlorophenoxy herbicides". Toxicol Rev. 23 (2): 65–73. doi:10.2165/00139709-200423020-00001. PMID 15578861.