Chondroitin as a supplement is now commonly used in treating the joint disease of osteoarthritis as well as glucosamine. In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine. Chondroitin's effect toward the articular cartilage integrity as it is part of the proteoglycan molecules. The cartilage proteoglycan synthesis can speed up as chondroitin is going through the pathway of the alimentary canal. Research has been conducted to show the effectiveness of chondroitin and results indicate that it helps to manage pain in knee and hip, slow down the progression and also recovery. However, the effectiveness of the drugs is still doubtful.
- Chondroitin at the US National Library of Medicine Medical Subject Headings (MeSH)
- Vasiliadis, Haris S; Tsikopoulos, Konstantinos (2017). "Glucosamine and chondroitin for the treatment of osteoarthritis". World Journal of Orthopedics. 8 (1): 1. doi:10.5312/wjo.v8.i1.1. ISSN 2218-5836. PMC 5241539. PMID 28144573.
- Tavakol, Kamran. "Glucosamine and Chondroitin for Treatment of Osteoarthritis: A Systematic Quality Assessment and Meta-analysis". Physical Therapy. 80 (10): 1049.
- Zhu, Xiaoyue; Sang, Lingli; Wu, Dandong; Rong, Jiesheng; Jiang, Liying (December 2018). "Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials". Journal of Orthopaedic Surgery and Research. 13 (1): 170. doi:10.1186/s13018-018-0871-5. ISSN 1749-799X. PMC 6035477. PMID 29980200.