Chris Kelly may refer to:
- Chris Kelly (jazz) (1890–1929), American jazz trumpeter
- Chris Kelly (composer), Canadian music composer and film producer
- Chris "Mac Daddy" Kelly (1978–2013), member of American rap duo Kris Kross
- Chris Kelly, guitar player for Stars Underground
- Chris Kelly (American politician) (born 1946), American politician
- Chris Kelly (British politician) (born 1978), Conservative MP for Dudley South 2010–2015
- Chris Kelly (footballer, born 1887), English football player
- Chris Kelly (footballer, born 1948), English football player
- Chris Kelly (ice hockey), Canadian hockey player
- Chris Kelly (entrepreneur), executive at Facebook
- Chris Kelly (TV presenter) (born 1940), former presenter of Food and Drink and Wish You Were Here...?
- Chris Kelly (writer), American writer for SNL and director of Other People
- Chris "Casper" Kelly (writer), American writer, television director, and producer.
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