Lake first became recognized for his bootleg remixes of The Prodigy's "Climbatize", Leftfield's "Phat Planet", and Eurythmics "Sweet Dreams". which he did under the alias "Cristophe D'Abuc". His 2006 track with vocals from Laura V, "Changes", reached the UK Singles Chart, peaking at #27. "Changes" was first released in 2005 on Alternative Route Recordings and was licensed to Universal Music for a full worldwide release in Summer 2006. It reached #10 on Billboard's Hot Dance Airplay chart. His 2007 single, "Carry Me Away" (featuring Emma Hewitt), topped the Billboard Hot Dance Airplay Chart. He scored his third consecutive top ten hit on the US dance chart with "Only One". "If You Knew" featuring Nastala, became his fourth consecutive top ten single on the US dance chart. A debut album is planned for release in 2009.
Lake has been a guest DJ on many radio shows such as Pete Tong's Radio 1. Tong hailed Lake as the "best thing to come out of Scotland since Mylo."
Chris Lake runs two labels: Rising Music and Rising Trax. For in-studio mixing, Lake uses Logic Pro and Ableton. He is managed by Brett Fischer.