Christopher Shaw (neurologist)

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Chris E Shaw
Christopher Edward Dennistoun Shaw[1]

27 March 1960[2]
Alma mater
Spouse(s)Pinar Bagci[2]
Childrenone son; one daughter[2]
  • Sheila Essey Award
Scientific career
Doctoral advisorAlastair Compston

Christopher Edward Dennistoun Shaw MBChB, MD, FRACP, FRCP (Hon), FMedSci, FANA[3] (born 1960) is Professor of Neurology and Neurogenetics at the Institute of Psychiatry, Psychology and Neuroscience, King's College London.[3] He is also Head of the Department of Basic and Clinical Neuroscience, Director of the Maurice Wohl Clinical Neuroscience Institute at King's College London[3] and an Honorary Consultant Neurologist and Neurogeneticist at King's College Hospital.[4] His major research interest is in the genetic, molecular and cellular basis of motor neuron diseases such as amyotrophic lateral sclerosis (ALS).[5][6]


Shaw conducted his clinical training in general medicine and neurology in New Zealand. In 1992, he began his doctoral studies on Wellcome Trust Fellowship with Professor Alastair Compston at the University of Cambridge.[3]


Shaw moved to the Institute of Psychiatry (now Institute of Psychiatry, Psychology and Neuroscience) and started collaborating with Professor Nigel Leigh in 1995.[3][4][7] Research led by Shaw has identified mutations in two genes causing ALS, namely TARDBP[8][9] and FUS.[10][11]


  1. ^ "Science: 'Who's who'?". Retrieved 12 April 2016.
  2. ^ a b c "SHAW, Christopher Edward Dennistoun (born 1960), Professor of Neurology and Neurogenetics, King's College London, since 2004 : Who's Who - oi". Who's Who. Oxford University Press. doi:10.1093/ww/9780199540884.013.u245495. Retrieved 12 April 2016.
  3. ^ a b c d e "Chris Shaw". Biomedical Research Centre. National Institute for Health Research. Retrieved 8 April 2016.
  4. ^ a b "Research". Racing 4 MND. Racing4MND. Retrieved 8 April 2016.
  5. ^ "Professor Christopher Shaw". King's College London. Retrieved 8 April 2016.
  6. ^ "Christopher Shaw". Project MinE. Retrieved 8 April 2016.
  7. ^ Fallik, Dawn (July 2012). "IN THE FIELD: Sheila Essey Awardee Christopher Shaw, MBChB, MD: On Taking the Back Roads to Unraveling ALS Genetics". Neurology Today. 12 (13): 28–29. doi:10.1097/01.NT.0000416339.28519.b6. Retrieved 8 April 2016.
  8. ^ Sreedharan, J.; Blair, I. P.; Tripathi, V. B.; Hu, X.; Vance, C.; Rogelj, B.; Ackerley, S.; Durnall, J. C.; Williams, K. L.; Buratti, E.; Baralle, F.; de Belleroche, J.; Mitchell, J. D.; Leigh, P. N.; Al-Chalabi, A.; Miller, C. C.; Nicholson, G.; Shaw, C. E. (21 March 2008). "TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis". Science. 319 (5870): 1668–1672. doi:10.1126/science.1154584. PMID 18309045.
  9. ^ "Breakthrough in the study of motor neurone disease". The Independent. Retrieved 8 April 2016.
  10. ^ Vance, C.; Rogelj, B.; Hortobagyi, T.; De Vos, K. J.; Nishimura, A. L.; Sreedharan, J.; Hu, X.; Smith, B.; Ruddy, D.; Wright, P.; Ganesalingam, J.; Williams, K. L.; Tripathi, V.; Al-Saraj, S.; Al-Chalabi, A.; Leigh, P. N.; Blair, I. P.; Nicholson, G.; de Belleroche, J.; Gallo, J.-M.; Miller, C. C.; Shaw, C. E. (27 February 2009). "Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6". Science. 323 (5918): 1208–1211. doi:10.1126/science.1165942. PMC 4516382. PMID 19251628.
  11. ^ "Motor neurone disease 'gene clue'". BBC. 28 February 2009. Retrieved 8 April 2016.