Chromosome 9 (human)

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Chromosome 9 (human)
Human male karyotpe high resolution - Chromosome 9 cropped.png
Human chromosome 9 pair after G-banding.
One is from mother, one is from father.
Human male karyotpe high resolution - Chromosome 9.png
Chromosome 9 pair in human male karyogram.
Length (bp) 138,394,717 bp
Number of genes 1,742
Type Autosome
Centromere position Submetacentric[1]
RefSeq NC_000009
GenBank CM000671
Map of Chromosome 9
Ideogram of human chromosome 9. Mbp means mega base pair. See locus for other notation.

Chromosome 9 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome, as they normally do with all chromosomes. Chromosome 9 spans about 138 million base pairs of nucleic acids (the building blocks of DNA) and represents between 4 and 4.5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 9 likely contains between 800 and 1,200 genes.


The following are some of the genes located on chromosome 9:

  • ABO: ABO histo-blood group glycosyltransferases
  • ACTL7A: encoding protein Actin-like protein 7A
  • ADAMTS13: ADAM metallopeptidase with thrombospondin type 1 motif, 13
  • ALAD: aminolevulinate, delta-, dehydratase
  • ALS4: amyotrophic lateral sclerosis 4
  • ASS: argininosuccinate synthetase
  • CCL21: chemokine (C-C motif) ligand 21, SCYA21
  • CCL27: chemokine (C-C motif) ligand 27, SCYA27
  • C9orf58/AIF1L: encoding protein Allograft inflammatory factor 1-like
  • C9orf78: encoding protein Uncharacterized protein C9orf78
  • C9orf82: encoding protein Uncharacterized protein C9orf82
  • C9orf91: encoding protein C9orf91
  • C9orf135: encoding protein Chromosome 9 open reading frame 135
  • COL5A1: collagen, type V, alpha 1
  • ENG: endoglin (Osler-Rendu-Weber syndrome 1)
  • FIBCD1: encoding protein Fibrinogen C domain containing 1
  • FXN: frataxin
  • GALT: galactose-1-phosphate uridylyltransferase
  • GLE1L: Nucleoporin GLE1
  • GRHPR: glyoxylate redasductase/hydroxypyruvate reductase
  • IKBKAP: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • MGC50722: Protein MGC50722, Uncharacterized Protein LOC399693
  • TGFBR1: transforming growth factor beta, receptor type I
  • TMC1: transmembrane channel-like 1
  • TSC1: tuberous sclerosis 1

Diseases and disorders[edit]

The following diseases are some of those related to genes on chromosome 9:


  1. ^ "Table 2.3: Human chromosome groups". Human Molecular Genetics (2nd ed.). Garland Science. 1999.