Chronotherapy (treatment scheduling)
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|Chronotherapy (treatment scheduling)|
Chronotherapy, also called chronotherapeutics or chronotherapeutic drug delivery, refers to the use of circadian or other rhythmic cycles of a condition's symptoms and/or of the individual being treated in the application of therapy. Examples of this are treatments of psychiatric and somatic diseases that are administered according to a schedule that corresponds to these rhythms in order to maximize effectiveness and minimize side effects of the therapy.
Chronotherapy is used in various clinical fields such as the treatments of asthma,[non-primary source needed] cancer,[medical citation needed] hypertension, and several , seasonal affective disorder[medical citation needed] and bipolar disorder.
In the treatment of psychiatric conditions including bipolar depression, a form of chronotherapy combining intermittent sleep deprivation and morning bright light has shown efficacy and relative tolerability in a number of controlled studies.
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...drug availability is timed to match rhythms of disease in order to optimize therapeutic outcomes and minimize side effects.
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