Cioteronel

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Cioteronel
Cioteronel.svg
Systematic (IUPAC) name
4-(5-methoxyheptyl)-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-one
Identifiers
CAS Number 89672-11-7
ATC code None
PubChem CID 55994
ChemSpider 50555
UNII 1RTH95874Z
ChEMBL CHEMBL2104105
Chemical data
Formula C16H28O2
Molar mass 252.39232 g/mol

Cioteronel (INN, USAN) (developmental code name CPC-10997; former tentative brand names Cyoctol, Ethocyn, X-Andron) is a non-steroidal antiandrogen that was never marketed.[1][2][3] It was under development for the topical treatment of androgenetic alopecia (male pattern baldness) and acne and the oral treatment of benign prostatic hyperplasia between 1989–2001 and reached phase III clinical trials for acne and phase II studies for androgenetic alopecia but was ultimately discontinued due to poor efficacy.[3][1]

See also[edit]

References[edit]

  1. ^ C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 570–. ISBN 978-0-412-46630-4. 
  2. ^ Daniel Lednicer (21 November 1994). The Organic Chemistry of Drug Synthesis. John Wiley & Sons. pp. 11–. ISBN 978-0-471-58959-4. 
  3. ^ a b Tiwari, Atul; Krishna, N S; Nanda, Kamna; Chugh, Anita (2005). "Benign prostatic hyperplasia: an insight into current investigational medical therapies". Expert Opinion on Investigational Drugs 14 (11): 1359–1372. doi:10.1517/13543784.14.11.1359. ISSN 1354-3784.