Ancestry and Family
Tisamenis was of Athenian descent. Her ancestry can be traceable to the Athenian noble woman Elpinice (a half sister of statesman Cimon and daughter of politician Miltiades the Younger). She had an ancestor four generations removed from her called Polycharmus. Polycharmus from 9/8 BC-22/23, could have served as an Archon of Athens. Her family bears the Roman family name, Claudius. There is a possibility that a paternal ancestor of hers, received Roman citizenship, from an unknown member of the Claudius gens.
Tisamenis was born to a distinguished and very rich family of consular rank. She was the daughter of Roman Senator Tiberius Claudius Atticus Herodes and the wealthy heiress Vibullia Alcia Agrippina. Tisamenis had two brothers: the prominent Greek Sophist Lucius Vibullius Hipparchus Tiberius Claudius Atticus Herodes and Tiberius Claudius Atticus Herodianus. Her maternal grandparents were Claudia Alcia and Lucius Vibullius Rufus, while her paternal grandfather was Hipparchus and his unnamed wife.
Her parents are related and are uncle and niece. Her maternal grandmother with her father is sister and brother. Her maternal uncle Lucius Vibullius Hipparchus was an Archon of Athens in the years 99-100  and her maternal cousin, Publius Aelius Vibullius Rufus was an Archon of Athens between 143-144.
According to the French Historian Christian Settipani, Tisamenis was born about ca. 100  in an unknown place in Greece. She spent her childhood travelling between Greece and Italy. Modern Historians have argued that Tisamenis could have married a Greek Aristocratic in Sparta from the Achaea Province. The name of Tisamenis has been found as a testamentary disposition on an erection of a family statue-group in her marital home-city. According to Settipani, Tisamenis married an unnamed Roman Aristocrat, by whom she had a daughter called Claudia (b. ca 120), who might have been the mother of Roman Emperor Gordian I.
- Pomeroy, The murder of Regilla: a case of domestic violence in antiquity
- Day, An economic history of Athens under Roman domination p. 238
- Wilson, Herodes Atticus, Encyclopedia of Ancient Greece p.p. 349-350
- Graindor, Un milliardaire antique p. 29
- fr:Continuité gentilice et continuité sénatoriale dans les familles sénatoriales romaines à l'époque impériale (Christian Settipani)|Continuité gentilice et continuité sénatoriale dans les familles sénatoriales romaines à l'époque impériale, 2000
- Cartledge, Hellenistic and Roman Sparta: a tale of two cities p. 175
- Day, J., An economic history of Athens under Roman domination, Ayers Company Publishers, 1973
- Graindor, P., Un milliardaire antique, Ayers Company Publishers, 1979
- Continuité gentilice et continuité sénatoriale dans les familles sénatoriales romaines à l'époque impériale, 2000
- Cartledge, P., Hellenistic and Roman Sparta: a tale of two cities, Routledge, 2002
- Wilson, N.G., Encyclopedia of Ancient Greece, Routledge 2006
- Pomeroy, S.B., The murder of Regilla: a case of domestic violence in antiquity, Harvard University Press, 2007