Claus Manniche

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Claus Manniche (born June 21, 1956) is a Danish rheumatologist, Consultant and Professor. His main research interests are clinical databases in back pain and research methodology. He has authored more than 120 journal articles[1] and co-authored several books.[1]

Life and career[edit]

Claus Manniche was born in Kalundborg, Denmark. He studied medicine at the University of Copenhagen, graduating in 1982 and gained his license to practice in 1985. After gaining a law degree in 1988, he focused on the field of back pain and rheumatology,[2] becoming a specialist Doctor in the latter area in 1994. In 1998 Claus Manniche was appointed as Professor and Director of the Spine Center of Southern Denmark.[2]

Professor Manniche has been a part of several influential committees and research groups including the Danish Rheumatology Society, the Copenhagen Back Research Association and was more recently appointed by the Minister of Health as a member of a specialist committee investigating the prevention of back problems.[2]

Claus Manniche has been the recipient of the Scandinavian Journal of Rheumatology’s 40th Nordic Anniversary Prize in 1995. Two clinics that Professor Manniche developed have also been recognized: the outpatient back clinic at Aarhus County Hospital (Denmark) received the ‘Quality Award for the year 1996, Aarhus Amt’; the Back Center at Fyn was a recipient of the Danish Chiropractors’ Association honorary award in 2008.[2]


Published in The Lancet 1988 [1][3] one of the first randomized studies demonstrating convincing effects of exercise therapy in nonspecific back pain patients.[2] This paper was groundbreaking regarding active spine rehabilitation worldwide. Developed a method for registration of pain and distinction between different types of pain: Low Back Pain Rating Scale,[1][4] which is still used in research projects around the world.[1][4] Has contributed to the discovery of the so-called Modic changes.[1][5][6][7]


  1. ^ a b c d e f "". Retrieved 8 December 2013. 
  2. ^ a b c d e Manniche, Claus (2013). "Interview: Back pain research". Clinical Practice. 10 (6): 691–4. doi:10.2217/cpr.13.62. 
  3. ^ Manniche, Claus; Bentzen, Lis; Hesselse, Grete; Christensen, Inge; Lundberg, Eva (1988). "Clinical Trial of Intensive Muscle Training for Chronic Low Back Pain". The Lancet. 332 (8626–8627): 1473–1476. doi:10.1016/S0140-6736(88)90944-0. 
  4. ^ a b Manniche, Claus; Asmussen, Karsten; Lauritsen, Birgitte; Vinterberg, Henrik; Kreiner, Svend; Jordan, Alan (1994). "Low Back Pain Rating scale: Validation of a tool for assessment of low back pain". Pain. 57 (3): 317–26. doi:10.1016/0304-3959(94)90007-8. PMID 7936710. 
  5. ^ Albert, H.B.; Kjaer, P.; Jensen, T.S.; Sorensen, J.S.; Bendix, T.; Manniche, Claus (2008). "Modic changes, possible causes and relation to low back pain". Medical Hypotheses. 70 (2): 361–8. doi:10.1016/j.mehy.2007.05.014. PMID 17624684. 
  6. ^ Albert, Hanne B.; Manniche, Claus (2007). "Modic changes following lumbar disc herniation". European Spine Journal. 16 (7): 977–82. doi:10.1007/s00586-007-0336-8. PMC 2219661Freely accessible. PMID 17334791. 
  7. ^ Albert, Hanne B.; Sorensen, Joan S.; Christensen, Berit Schiott; Manniche, Claus (2013). "Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): A double-blind randomized clinical controlled trial of efficacy". European Spine Journal. 22 (4): 697–707. doi:10.1007/s00586-013-2675-y. PMC 3631045Freely accessible. PMID 23404353.