Clentiazem

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Clentiazem
Clentiazem structure.svg
Names
IUPAC name
acetic acid [(2S,3S)-8-chloro-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] ester
Identifiers
111659-76-8 YesY
3D model (Jmol) Interactive image
ChemSpider 51418 N
PubChem 57026
UNII 40DK034DRC YesY
Properties
C22H25ClN2O4S
Molar mass 448.9629
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Clentiazem is a calcium channel blocker.[1]

It is a chloride derivative of diltiazem.[2]

References[edit]

  1. ^ Giasson S, Garceau D, Homsy W, Dumont L (October 1995). "Pharmacodynamics and pharmacokinetics of clentiazem and diltiazem in closed-chest anesthetized dogs". Cardiovasc Drugs Ther. 9 (5): 685–92. doi:10.1007/BF00878551. PMID 8573551. 
  2. ^ Dagenais F, Hollmann C, Buluran J, Cartier R (October 1995). "Clentiazem and diltiazem preserve endothelium-dependent relaxation following global rat heart ischemia". Can J Cardiol. 11 (9): 816–22. PMID 7585280.