Clive McCay

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Clive McCay
Born(1898-03-21)21 March 1898
Died8 June 1967(1967-06-08) (aged 69)
Known forcalorie restriction life extension
Scientific career
InstitutionsCornell University

Clive Maine McCay (1898—1967) was an American biochemist, nutritionist, gerontologist, and professor of animal husbandry at Cornell University from 1927-1963. His main interest was the influence of nutrition on aging.[1] He is best known for his work in proving that caloric restriction increases the life span of rats, which is seen as seminal in triggering further research and experiments in the field of nutrition and longevity.[2] Scientists are still trying to understand the connection between caloric restriction and longevity.

Following his discovery between a low calorie diet and longevity, McCay played a prominent role in the development of nutritionally-sound rations during World War II, and the creation of Cornell Bread, a type of high protein, high vitamin bread meant to echo the same high protein vitamin meal he fed to his mice in longevity experiments. His further research centered on canine nutrition, fluoride and its use in water treatment, and parabiosis.[3] A 1957 study on fluoridation showed that low levels (1-10 ppm) of sodium fluoride added to the drinking water of rats did not have carie-protective effects.[4]


  1. ^ Clive M. McCay and Jeanette B. McCay - History of Work with Soyfoods, the New York State Emergency Food Commission, Improved Bread, and Extension of Lifespan (1927-2009): Extensively Annotated Bibliography and Sourcebook. Soyinfo Center. 2009. p. 55. ISBN 978-1-928914-27-3. Retrieved 12 April 2013.
  2. ^ McCay, C. M.; Crowell, Mary F. (November 1934). "Prolonging the Life Span". The Scientific Monthly. 39 (5): 405–414. Bibcode:1934SciMo..39..405M. JSTOR 15813.
  3. ^ "Cornell Library Guide to the Clive McCay Papers, 1920-1967". Cornell Library. Retrieved 12 April 2013.
  4. ^ United States. Congress. Senate. Committee on Labor and Public Welfare (1959). National Organizations in the Field of Aging: Hearings Before the Subcommittee on Problems of the Aged and Aging of the Committee on Labor and Public Welfare, United States Senate, Eighty-sixth Congress, First Session, August 4, 5, and 6, 1959. U.S. Government Printing Office. p. 232. Retrieved 12 April 2013.

External links[edit]

McDonald, Roger B.; Ramsey, Jon J. (July 2010). "Honoring Clive McCay and 75 years of caloric restriction research". Journal of Nutrition. 140 (7). doi:10.3945/jn.110.122804. ISSN 1541-6100. PMC 2884327. Retrieved 2011-12-17.