Clocortolone

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Clocortolone pivalate
Clocortolone.svg
Systematic (IUPAC) name
[2-(9-chloro-6-fluoro-11-hydroxy- 10,13,16-trimethyl- 3-oxo-7,8,11,12,14,15,16,17- octahydro- 6H-cyclopenta[a]phenanthren-17-yl)- 2-oxo-ethyl] 2,2-dimethylpropanoate
Clinical data
Trade names Cloderm
AHFS/Drugs.com Consumer Drug Information
Pregnancy
category
  • US: C (Risk not ruled out)
Legal status
Routes of
administration
Topical
Identifiers
CAS Registry Number 34097-16-0 YesY
ATC code D07AB21
PubChem CID: 5282493
DrugBank DB00838 YesY
ChemSpider 4445634 YesY
UNII QBL8IZH14X YesY
KEGG D02287 YesY
ChEBI CHEBI:59583 YesY
ChEMBL CHEMBL1201366 N
Chemical data
Formula C27H36ClFO5
Molecular mass 495.023 g/mol
 N (what is this?)  (verify)

Clocortolone (Cloderm) is a topical steroid.[1] It is used in the form of an ester, clocortolone pivalate, and applied as a cream.[2] It is used for the treatment of dermatitis and is considered a medium-strength corticosteroid. It is unusual among steroids in that it contains a chlorine atom and a fluorine atom.

See also[edit]

References[edit]

  1. ^ Nierman, M. M. (1981). "Safety and efficacy of clocortolone pivalate 0.1 percent cream in the treatment of atopic dermatitis, contact dermatitis, and seborrheic dermatitis". Cutis; cutaneous medicine for the practitioner 27 (6): 670–671. PMID 6453703.  edit
  2. ^ Drugs.com: Clocortolone topical