Clorobiocin

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Clorobiocin
Clorobiocin.png
Clinical data
SynonymsChlorobiocin
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC35H37ClN2O11
Molar mass697.13 g/mol g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Clorobiocin is an aminocoumarin antibacterial that inhibits the enzyme DNA gyrase.[2][3]

References[edit]

  1. ^ [1], http://www.drugbank.ca/drugs/DB03966.
  2. ^ Pojer, F.; Wemakor, E.; Kammerer, B.; Chen, H.; Walsh, C.; Li, S.; Heide, L. (2003). "CloQ, a prenyltransferase involved in clorobiocin biosynthesis". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2316–2321. Bibcode:2003PNAS..100.2316P. doi:10.1073/pnas.0337708100. PMC 151338. PMID 12618544.
  3. ^ Heide, L. (2009). "Genetic engineering of antibiotic biosynthesis for the generation of new aminocoumarins". Biotechnology Advances. 27 (6): 1006–1014. doi:10.1016/j.biotechadv.2009.05.017. PMID 19463934.