Clostridium difficile
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Clostridium difficile may refer to:
- Clostridium difficile (bacteria) also known as C. difficile, C. diff, or sometimes CDF/cdf, a species of Gram-positive spore-forming bacteria
- Clostridium difficile infection
- Clostridium difficile colitis, colitis (inflammation of the large intestine) resulting from infection with Clostridium difficile bacteria