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Clovis Oncology

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Clovis Oncology is a small pharmaceutical company which mainly markets products for treatment in oncology.[1] Depomed was founded in 2009 and is headquartered in Dover, Colorado.[2] The company is a publicly traded company on NASDAQ under the symbol "CLVS" [3] and is in the NASDAQ Biotechnology Index[4] with several products in its product pipeline.[5]

Pipeline

Its products include:

Rociletinib

It is developing rociletinib,[6] which is in development as a treatment for non-small cell lung cancer.[1][7][8][9]

A phase III trial has completed and in April 2016 an FDA committee will consider recommending it for marketing approval.[10] If approved it would compete with AstraZeneca's Tagrisso (osimertinib).[10]

Rucaparib

Rucaparib is a PARP inhibitor in Phase II and III clinical trials for advanced ovarian cancer.[11]

Lucitanib

Lucitanib is a VEGFR inhibitor.[12]

References

  1. ^ a b "Clovis Oncology: A Winning Or Losing Lottery Ticket?". Forbes. 2015-11-16. Retrieved 2016-01-04.
  2. ^ "CLVS Profile". finance.yahoo.com.
  3. ^ "Clovis Oncology Inc". www.marketwatch.com. Retrieved 4 January 2016.
  4. ^ "Overview NBI". nasdaq.com. Retrieved 4 January 2016.
  5. ^ "Clovis Oncology - Products & Companion Diagnostics". Clovisoncology.com. 9 March 2015. Archived from the original on March 9, 2015. Retrieved 4 January 2016. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  6. ^ Williams, Sean (23 December 2015). "A Festivus for the Invest in Us -- It's Time for the Airing of Grievances". Fox Business. Retrieved 4 January 2016.
  7. ^ Wallace, Alicia. "Clovis Oncology stock bludgeoned after delay in cancer drug approval". www.denverpost.com. Retrieved 4 January 2016.
  8. ^ "hClovis Oncology Announces Regulatory Update for Rociletinib NDA Filing". www.reuters.com. Retrieved 4 January 2016.
  9. ^ "FDA Requests Additional Data for Rociletinib in EGFR T790M-Mutant NSCLC". OncLive. 2015-11-16. Retrieved 2016-01-04.
  10. ^ a b Investors doubt efficacy of Clovis lung cancer med rociletinib, shares off 11%. April 2016
  11. ^ Rucaparib at Clovis
  12. ^ Lucitanib at Clovis