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Co-amilofruse (BAN) is a nonproprietary name used to denote a combination of amiloride and the formerly named frusemide (now the INN termed furosemide). Co-amilofruse is a treatment for fluid retention (oedema), either in the legs (peripheral edema) or on the lungs (pulmonary oedema). The stronger furosemide loop diuretic has a tendency to cause low potassium levels (hypokalaemia) that may be prevented by the potassium-sparing effects of amiloride.
Two strengths of co-amilofruse are available:
- 2.5 mg amiloride with 20 mg furosemide, BAN of Co-amilofruse 2.5/20 (brand name Frumil LS)
- 5 mg amiloride with 40 mg furosemide, BAN of Co-amilofruse 5/4-0 (brand name Frumil)
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