Coclaurine

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Coclaurine
Coclaurine.svg
Names
IUPAC name
(1S)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol
Identifiers
486-39-5
ChemSpider 141028
Jmol 3D model Interactive image
PubChem 160487
Properties
C17H19NO3
Molar mass 285.34 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Coclaurine is a nicotinic acetylcholine receptor antagonist[citation needed] which has been isolated from a variety of plant sources including Nelumbo nucifera, Sarcopetalum harveyanum,[1] Ocotea duckei,[2] and others. It belongs to the class of tetrahydroisoquinoline alkaloids. Dimerization of coclaurine leads to the biscoclaurine alkaloids such as cepharanthine.

References[edit]

  1. ^ Sowemimo BO, Beal JL, Doskotch RW, Svoboda GH (1972). "The isolation of stepharine and coclaurine from Sarcopetalum harveyanum". Lloydia 35 (1): 90–91. PMID 5037484. 
  2. ^ I.G da Silva; J.M Barbosa-Filho; M.S da Silva; C.D.G de Lacerda; E.V.L da-Cunha (2002). "Coclaurine from Ocotea duckei". Biochemical Systematics and Ecology 30 (9): 881–883. doi:10.1016/s0305-1978(02)00024-8.