Codeine methylbromide

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Codeine methylbromide
Codeine methylbromide.png
Clinical data
AHFS/ Monograph
Legal status
Legal status
Synonyms Codeine bromomethylate, 125-27-9, DEA No. 9070
CAS Number
PubChem CID
Chemical and physical data
Formula C19H24BrNO3
Molar mass 394.30 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Codeine methylbromide (Eucodin) is the bromomethane (methylbromide) salt of codeine. Its possession is prohibited in many jurisdictions. It is considered a Schedule I controlled substance in the United States, with a DEA ACSCN of 9070 and nil annual aggregate manufacturing quota.[1] as of 2014. As it is used in a different way than basic salts of codeine like the phosphate or hydrochloride owing to its below-mentioned dual action, it is considered to be a different drug related to codeine rather than merely a salt of it in many contexts.[2]

Also known by the genericised trade name eucodeine, and the salt name also sometimes given as methobromide, this drug was first synthesised in Austria-Hungary in 1903. As it is a bromide in addition to a codeine salt, it has a dual mechanism of action and is indicated for pain with insomnia or nervousness and violent coughing.[3] This codeine-based bromide also has morphine, dihydrocodeine, dihydromorphine, hydromorphone, isocodeine, hydrocodone, and other such analogues; also, there are codeine-based barbiturates and salicylates.[4]