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Systematic (IUPAC) name
CAS Registry Number 72060-05-0
ATC code None
PubChem CID: 172964
ChemSpider 151049
Chemical data
Formula C23H29NO3
Molecular mass 367.481 g/mol

Conorfone (INN; TR-5109), also known as conorphone and codorphone, as well as conorphone hydrochloride (USAN), is an opioid analgesic that was never marketed.[1] It is an analogue of hydrocodone substituted with an 8-ethyl group and an N-cyclopropylmethyl group. It acts as a mixed agonist-antagonist at the μ-opioid receptor, and is slightly more potent than codeine in analgesic effects but associated with somewhat greater side effects.[2]

See also[edit]


  1. ^ F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 514. ISBN 978-0-412-46630-4. Retrieved 12 May 2012. 
  2. ^ Dionne RA, Wirdezk PR, Butler DP, Fox PC (1984). "Comparison of conorphone, a mixed agonist-antagonist analgesic, to codeine for postoperative dental pain". Anesthesia Progress 31 (2): 77–81. PMC 2515536. PMID 6597688.