Collagen, type XIX, alpha 1

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Aliases COL19A1, COL9A1L, D6S228E, collagen type XIX alpha 1, collagen type XIX alpha 1 chain
External IDs MGI: 1095415 HomoloGene: 55608 GeneCards: COL19A1
RNA expression pattern
PBB GE COL19A1 211011 at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 6: 69.87 – 70.21 Mb Chr 1: 24.26 – 24.59 Mb
PubMed search [1] [2]
View/Edit Human View/Edit Mouse

Collagen alpha-1(XIX) chain is a protein that in humans is encoded by the COL19A1 gene.[3][4][5]

This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced.[5]


  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Myers JC, Sun MJ, D'Ippolito JA, Jabs EW, Neilson EG, Dion AS (Mar 1993). "Human cDNA clones transcribed from an unusually high-molecular-weight RNA encode a new collagen chain". Gene. 123 (2): 211–7. doi:10.1016/0378-1119(93)90126-N. PMID 7916703. 
  4. ^ Gerecke DR, Olson PF, Koch M, Knoll JH, Taylor R, Hudson DL, Champliaud MF, Olsen BR, Burgeson RE (Jul 1997). "Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13". Genomics. 41 (2): 236–42. doi:10.1006/geno.1997.4638. PMID 9143499. 
  5. ^ a b "Entrez Gene: COL19A1 collagen, type XIX, alpha 1". 

Further reading[edit]