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Columbia Basin may refer to:
- Columbia Plateau, the geographic region in the Pacific Northwest commonly referred to as the Columbia Basin
- Columbia Plateau (ecoregion), a desert ecoregion in the U.S. states of Oregon and Washington
- Columbia River drainage basin, a drainage basin covering parts of U.S. and Canada
- Columbia River Basalt Group the geological region corresponding to the Columbia Plateau
disambiguation page lists articles associated with the title Columbia Basin.
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