"Come Go with Me" became Exposé's first single to reach the US Billboard Hot 100 chart, where it peaked at number five in April 1987 and remained in the Top 40 for 12 weeks. The single also peaked at number 19 in Canada.
In 1985 Exposé had two club hits, "Point of No Return" and "Exposed to Love". Between 1985 and 1986, the three original members of Exposé left the group and were replaced by Jurado, Bruno and Curless. These new members re-recorded vocals on "Point of No Return" and both songs were included on the album. Although "Come Go with Me" was the third single released from Exposure, the other two songs were familiar to fans of the group and its music.
In the United States, "Come Go with Me" spent two weeks at the summit of the BillboardDance Club Songs chart in January 1987, becoming their second single to achieve such feat. The 12" single also reached number two on the BillboardDance/Electronic Singles Sales chart.