Complement component 9
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Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system.[5] C9 is a member of the complement membrane attack complex (MAC) and induces pores on cell membranes, causing lysis. There are 10-16 molecules of C9 in a single membrane attack complex (MAC), along with one of each of the complement components C5b, C6, C7 and C8.[6]
References[edit]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000113600 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022149 - Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Lint TF, Zeitz HJ, Gewurz H (November 1980). "Inherited deficiency of the ninth component of complement in man". J. Immunol. 125 (5): 2252–7. PMID 7430628.
- ^ Janeway, CA Jr; Travers P; Walport M; et al. (2001). "The complement system and innate immunity". Immunobiology: The Immune System in Health and Disease. New York: Garland Science. Retrieved 29 December 2017.
External links[edit]
- Complement+9 at the US National Library of Medicine Medical Subject Headings (MeSH)
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Complement component C9
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