The Connecticut gubernatorial election of 2006 occurred on November 7, 2006. The incumbent, Jodi Rell, became governor when John G. Rowland resigned in 2004. Rell, whose approval rating as of October 19, 2006, was 70% and her "net" approval rating (approval percentage less disapproval percentage) was 43% led DeStefano by a near 30-point margin, consistent with opinion polls leading up to the election. On November 7, the results were final, and Jodi Rell was elected Governor of Connecticut.
DeStefano defeated Stamford Mayor Dan Malloy in the Connecticut Democratic gubernatorial primary on August 8. As of 2018, this is the most recent time a Republican was elected Governor of Connecticut.