Pohlers comes from a football playing family. Her father played and her mother was once the top goal scorer in a regional league. She first played at the age of seven with FSV '67 Halle. In 1994, she moved to 1. FFC Turbine Potsdam. In the 2003 season, she played in the American professional league, WUSA, with the Atlanta Beat. In February 2007 she announced that she would be transferring to 1.FFC Frankfurt for the 2007–08 season. In 2013, playing for VfL Wolfsburg, she again became a Bundesliga champion, and on May 19 she scored a goal in Wolfsburg's 3-2 Cup Final win against her old team, Turbine Potsdam.