Corneodesmosin

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CDSN
Identifiers
Aliases CDSN, D6S586E, HTSS, HTSS1, HYPT2, PSS, S, PSS1, corneodesmosin
External IDs HomoloGene: 48005 GeneCards: CDSN
RNA expression pattern
PBB GE CDSN 206192 at fs.png

PBB GE CDSN 206193 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001264

n/a

RefSeq (protein)

NP_001255

n/a

Location (UCSC) Chr 6: 31.12 – 31.12 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Corneodesmosin is a protein that in humans is encoded by the CDSN gene.[2][3][4]

This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. During maturation of the cornified layers, the protein undergoes a series of cleavages, which are thought to be required for desquamation. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.[4]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ Simon M, Montezin M, Guerrin M, Durieux JJ, Serre G (Jan 1998). "Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes". J Biol Chem. 272 (50): 31770–6. doi:10.1074/jbc.272.50.31770. PMID 9395522. 
  3. ^ Zhou Y, Chaplin DD (Nov 1993). "Identification in the HLA class I region of a gene expressed late in keratinocyte differentiation". Proc Natl Acad Sci U S A. 90 (20): 9470–4. doi:10.1073/pnas.90.20.9470. PMC 47590Freely accessible. PMID 8415725. 
  4. ^ a b "Entrez Gene: CDSN corneodesmosin". 

Further reading[edit]