Coronary perfusion pressure

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Coronary perfusion pressure (CPP), also known as simply perfusion pressure, refers to the pressure gradient that drives coronary blood pressure, meaning the difference between the diastolic aortic pressure and the left ventricular end diastolic pressure. It is a term used mainly in research concerning cardiac arrest. In this context, it is assumed that the minimum CPP needed for a successful outcome is 15mm Hg.

CPP is a part of normal blood pressure that is specifically responsible for coronary blood flow. CPP is also, generally, a surrogate term for coronary blood flow.

During cardiac arrest, CPP is one of the most important variables associated with the likelihood of return of spontaneous circulation (ROSC), the restoration of a pulse. A CPP of at least 15 mmHg is thought to be necessary for ROSC.[1]


  1. ^ Sutton; et al. (August 2014). "Hemodynamic–directed cardiopulmonary resuscitation during in–hospital cardiac arrest". Resuscitation. 85 (8): 983–986. doi:10.1016/j.resuscitation.2014.04.015. PMC 4087068. PMID 24783998.
  • Marino, Paul L. (2007). "Disorders of circulatory flow". The ICU Book. Lippincott Williams & Wilkins. p. 287. ISBN 978-0-7817-4802-5.