Corydalis ambigua

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Corydalis ambigua
Corydalis ambigua.jpg
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
Order: Ranunculales
Family: Papaveraceae
Genus: Corydalis
Species: C. ambigua
Binomial name
Corydalis ambigua
Cham. & Schltdl.[1]

Corydalis ambigua is a tuberous early flowering east Asian flowering plant species. Its exact native range is obscure due to taxonomic confusion.[1] It is one of the sources of the drug tetrahydropalmatine.

Chemistry[edit]

Corydalis ambigua contains a variety of alkaloids including corynoline, acetylcorynoline d-corydalin, dl-tetrahydropalmatine, protopine, tetrahydrocoptisine, dl-tetrahydrocoptisine, d-corybulbine and allo-crytopine.[2][3][4][5]

Chemical derivatives of tetrahydroprotoberberines present in Corydalis ambigua have been studied as potential ways to increase pain tolerance and for treating drug addiction.[6] Further, they may represent a category of neurotransmitter stabilizers which have potential use in broad range of psychotic and neurological disorders.[6]

See also[edit]

References[edit]

  1. ^ a b "Corydalis ambigua information from NPGS/GRIN". USDA. 28 Nov 2001. Retrieved 2008-02-04. 
  2. ^ Zhu, Da-Yuan; et al. (1981). "IDENTIFICATION OF THE STRUCTURES OF CORYDALIS F, I, J AND K". Acta Chimica Sinica. 
  3. ^ Ma, W.g.; Fukushi, Y.; Tahara, S. (1999). "Fungitoxic alkaloids from Hokkaido Corydalis species". Fitoterapia. 70 (3): 258–265. doi:10.1016/S0367-326X(99)00045-3. 
  4. ^ Hiraoka, Noboru; et al. (2004). "Alkaloid production by somatic embryo cultures of Corydalis ambigua" (PDF). Plant Biotechnology. 21 (5): 361–366. doi:10.5511/plantbiotechnology.21.361. 
  5. ^ Zhu, Xing-Zu (1991). "Memórias do Instituto Oswaldo Cruz - Development of natural products as drugs acting on central nervous system". Memórias do Instituto Oswaldo Cruz. 86: 173. doi:10.1590/S0074-02761991000600039. 
  6. ^ a b Zhen X.-C. (2010). "Tetrahydroprotoberberines (THPBs) in neuropsychological disorders: Recent development and prospective (Abstract S-33.004)". International Journal of Neuropsychopharmacology. 13 (SUPPL. 1): 41. 

Further reading[edit]

  • Bhakuni, D. S.; Chaturvedi, Rekha (1983). "The Alkaloids of Corydalis meifolia". Journal of Natural Products. 46 (4): 466–70. PMID 6631434. doi:10.1021/np50028a006.