The tree typically grows to a height of 7 to 30 metres (23 to 98 ft) and forms a lignotuber. It has fibrous, crumbly and tessellated grey-brown bark with adult leaves are glossy green and are predominantly alternate with a blade that is lanceolate to falcate and 7.3 to 21 centimetres (3 to 8 in) long and 0.7 to 2.8 cm (0.28 to 1.10 in) wide with a base tapering to the petiole. The petioles are 0.9 to 2.3 cm (0.35 to 0.91 in) long.
It blooms between May and August producing cream-white flowers.
Corymbia nesophila has a disjunct distribution throughout the tropical north, found in the east Kimberley region of Western Australia, the top end and islands of the coast of the Northern Territory and on the Cape York Peninsula of Queensland. It grows on basalt or laterite on the lower slopes and flat areas with sandy or sandy-loam soils.
- "Corymbia nesophila (Blakely) K.D.Hill & L.A.S.Johnson". NT Flora. Northern Territory Government. Retrieved 6 October 2016.
- "Corymbia nesophila". FloraBase. Western Australian Government Department of Parks and Wildlife.