Corynebacterium glutamicum

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Corynebacterium glutamicum
C glutamicum visualized using scanning electron microscopy.tif
C. glutamicum under scanning electron microscopy.
Scientific classification
Binomial name
Corynebacterium glutamicum
Abe et al. 1967
  • Micrococcus glutamicus Kinoshita et al. 1958
  • Brevibacterium flavum Okumura et al. 1962

Corynebacterium glutamicum (previously known as Micrococcus glutamicus)[1] is a Gram-positive, rod-shaped bacterium that is used industrially for large-scale production of amino acids.[2] While originally identified in a screen for organisms secreting L-glutamate, mutants of C. glutamicum have also been identified that produce various other amino acids.[3]

Due to its industrial importance, several clones of C. glutamicum have been sequenced by both industry and academic groups.[2] Furthermore, small RNA data was obtained by RNA-Seq in C. glutamicum ATCC 13032.[4]


Corynebacterium glutamicum ATCC 14067 was previously known as Brevibacterium flavum.[5]

See also[edit]


  1. ^ Tatsumi, Nami; Inui, Masayuki (14 August 2012). Corynebacterium glutamicum: Biology and Biotechnology. Springer Science & Business Media. p. 336. ISBN 978-3-642-29857-8.
  2. ^ a b Kalinowski, J; Bathe, B; Bartels, D; Bischoff, N; Bott, M; et al. (4 September 2003). "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of l-aspartate-derived amino acids and vitamins". Journal of Biotechnology. 104 (1–3): 5–25. doi:10.1016/S0168-1656(03)00154-8. PMID 12948626.
  3. ^ Zahoor A; Lindner SN; Wendisch VF (October 2012). "Metabolic Engineering of Corynebacterium glutamicum Aimed at Alternative Carbon Sources and New Products". Computational and Structural Biotechnology Journal. 3 (4): 1–11. doi:10.5936/csbj.201210004. PMC 3962153. PMID 24688664.
  4. ^ Mentz, Almut; Neshat, Armin; Pfeifer-Sancar, Katharina; Pühler, Alfred; Rückert, Christian; Kalinowski, Jörn (2013-10-19). "Comprehensive discovery and characterization of small RNAs in Corynebacterium glutamicum ATCC 13032". BMC Genomics. 14: 714. doi:10.1186/1471-2164-14-714. ISSN 1471-2164. PMC 4046766. PMID 24138339.
  5. ^ Lv, Yangyong; Juanjun, Liao; Wu, Zhanhong; Han, Shuangyan; Lin, Yin; Zheng, Suiping (February 2012). "Genome Sequence of Corynebacterium glutamicum ATCC 14067, Which Provides Insight into Amino Acid Biosynthesis in Coryneform Bacteria". Journal of Bacteriology. 194 (3): 742–743. doi:10.1128/JB.06514-11. PMC 3264075. PMID 22247536.

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