Cowdry bodies

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Cowdry bodies are eosinophilic or basophilic[1] nuclear inclusions composed of nucleic acid and protein seen in cells infected with Herpes simplex virus, Varicella-zoster virus, and Cytomegalovirus. They are named after Edmund Cowdry.

There are two types of intranuclear Cowdry bodies:

  • Type A (as seen in herpes simplex, VZV, CMV infections and Yellow fever) [2]
  • Type B (as seen in infection with poliovirus), though it may seem that this is an antiquated and perhaps illusory type.[3]

Light microscopy is used for detection of Cowdry bodies.


  1. ^ "Cytomegalovirus (CMV) colitis". Retrieved 2019-04-11.
  2. ^ "Herpes Group (Cytomegalovirus, Herpes simplex, Varicella/Zoster, Epstein-Barr)". Retrieved 2009-01-02.
  3. ^