It is used as a connecting point for many small cities, towns, and other urbanizations located in the jungle. In the past it has served Brazilian destinations and Miami, Florida, USA but these scheduled flights are no longer available, though connections through the newly opened route to Panama are possible. There have been many ongoing talks of direct Cusco-Iquitos flights but there currently aren't any. On July 14, Panamanian airline Copa Airlines will begin flights between its hub at Tocumen International Airport in Panama City and Iquitos. This will mark the resumption of international air services to the Amazon city. The airport runways are fully paved. It has flights to other destinations in the country with various airlines.
It is the main gateway for tourists visiting the city of Iquitos, spectacular jungle lodges, and the Amazon Rainforest, the world's largest rain forest.