Cryogenic fuels are fuels that require storage at extremely low temperatures in order to maintain them in a liquid state. These fuels are used in machinery that operates in space (e.g. rocket ships and satellites) because ordinary fuel cannot be used there, due to absence of an environment that supports combustion (on earth, oxygen is abundant in the atmosphere, whereas in human-explorable space, oxygen is virtually non-existent). Cryogenic fuels most often constitute liquefied gases such as liquid hydrogen. 
Some rocket engines use regenerative cooling, the practice of circulating their cryogenic fuel around the nozzles before the fuel is pumped into the combustion chamber and ignited. This arrangement was first suggested by Eugen Sänger in the 1940s. The Saturn V rocket that sent the first manned missions to the moon used this design element, which is still in use today.
Russian aircraft manufacturer Tupolev developed a version of its popular Tu-154 design but with a cryogenic fuel system, designated the Tu-155. Using a fuel referred to as liquefied natural gas (LNG), its first flight was in 1989.
How they work
Cryogenic fuels can be placed into two categories: inert and flammable/combustible. Both types exploit the large liquid to gas volume ratio that occurs when liquid transitions to gas phase. The feasibility of cryogenic fuels is associated with what is known as a high mass flow rate. With regulation, the high density energy of cryogenic fuels are utilized to produce thrust in rockets and controllable consumption of fuel. The following sections provide further detail.
These types of fuels typically use the regulation of gas production and flow to power pistons in an engine. The large increases in pressure are controlled and directed toward the engine's pistons. The pistons move thanks to the mechanical power transformed from the monitored production of gaseous fuel A notable example can be seen in Peter Dearman's liquid air vehicle. Some common inert fuels include:
These fuels utilize the beneficial liquid cryogenic properties along with the flammable nature of the substance as a source of power. These types of fuels are well known primarily for their use in rockets including the Intercontinental ballistic missile. Some common inert fuels include:
- Liquid Hydrogen
- Liquid Natural Gas (LNG)
- Liquid Methane
Combustible cryogenic fuels offer much more utility than most inert fuels can by. Liquefied natural gas, as with any fuel, will only combust when properly mixed with right amounts of air. As for LNG, the bulk majority of efficiency depends on the methane number, which is the gas equivalent of the octane number.  This is determined based on the methane content of the liquefied fuel and any other dissolved gas, and varies as a result of experimental efficiencies.  Maximizing efficiency in combustion engines will be a result of determining the proper fuel to air ratio and utilizing the addition other hydrocarbons for added optimal combustion.
Current gas liquefying processes have been improving over the past decades with the advent of better machinery and control of system heat losses. Typical techniques take advantage of the fact that as the controlled pressure of a gas is released, the temperature of the gas dramatically cools. Enough pressurization and then subsequent depressurization can liquefy most gases first noticed via the Joule-Thomson effect. 
Liquefied Natural Gas
A key point to note is that while it is cost effective to liquefy natural gas for storage, transport, and use, roughly 10 to 15 percent of the gas gets consumed during the process.  The optimal process contains four stages of propane refrigeration and two stages of ethylene refrigeration. There can be the addition of an additional refrigerant stage, but the additional costs of equipment are not economically justifiable. Efficiency can be tied to the pure component cascade processes which minimize the overall source to sink temperature difference associated with refrigerant condensing. The optimized process incorporates optimized heat recovery along with the use of pure refrigerants. All process designers of liquefaction plants using proven technologies face the same challenge: to efficiently cool and condense a mixture with a pure refrigerant. In the optimized Cascade process, the mixture to be cooled and condensed is the feed gas. In the propane mixed refrigerant processes, the two mixtures requiring cooling and condensing are the feed gas and the mixed refrigerant. The chief source of inefficiency lies in the heat exchange train during the liquefaction process. 
Advantages and Disadvantages
Benefits of Cryogenic Fuels
- Cryogenic fuels are environmentally cleaner than gasoline or fossil fuels. Among other things, the greenhouse gas rate could potentially be reduced by 11%-20% using LNG as opposed to gasoline when transporting goods. 
- Along with their eco-friendly nature, they have the potential to significantly decrease transportation costs of inland products because of their abundance compared to that of fossil fuels. 
- Cryogenic fuels have a higher mass flow rate than fossil fuels and therefore produce more thrust and power when combusted for use in an engine. This means that engines will run farther on less fuel overall than modern gas engines. 
- Cryogenic fuels are non-pollutants and therefore, if spilled, are no risk to the environment. There will be no need to clean up hazardous waste after a spill. 
Potential Drawbacks of Cryogenic Fuels
- Some cryogenic fuels, like LNG are naturally combustible. Ignition of fuel spills could result in a large explosion. This is possible in the case of a car crash with an LNG engine. 
- Cryogenic storage tanks must be able to withstand large amounts of pressure. High pressure propellant tanks require thicker walls and stronger alloys which make the vehicle tanks heavier, thereby reducing performance and practicality. 
- Despite non-toxic tendencies, cryogenic fuels are denser than air. As such, they and can lead to asphyxiation. If leaked, the liquid will boil into a very dense, cold gas and if inhaled, could be fatal. 
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