Crystal arthropathy

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Crystal arthropathy

Crystal arthropathy is a class of joint disorder (called arthropathy) that is characterized by accumulation of tiny crystals in one or more joints. Polarizing microscopy and application of other crystallographic techniques have improved identification of different microcrystals including monosodium urate, calcium pyrophosphate dihydrate, calcium hydroxyapatite, and calcium oxalate.[1]

Types include:

Name Substance Birefringence
Gout[2] accumulation of uric acid negative
Chondrocalcinosis[3] aka Pseudogout accumulation of calcium pyrophosphate positive

Risk factors[edit]


Differential diagnosis[edit]


  1. ^ Mcgill NW (2000). "Gout and other crystal-associated arthropathies". Baillière's Clinical Rheumatology. 14 (3): 445–460. doi:10.1053/berh.2000.0087. PMID 10985980.
  2. ^ Choi H (May 2006). "Epidemiology of crystal arthropathy". Rheum. Dis. Clin. North Am. 32 (2): 255–73, v. doi:10.1016/j.rdc.2006.03.002. PMID 16716879.
  3. ^ Canhão H, Fonseca JE, Leandro MJ, et al. (2001). "Cross-sectional study of 50 patients with calcium pyrophosphate dihydrate crystal arthropathy". Clin. Rheumatol. 20 (2): 119–22. doi:10.1007/s100670170081. PMID 11346223. Archived from the original on 2001-05-17. Retrieved 2008-12-16.
  4. ^ Axford, DSc, MD, John S. "Rheumatic manifestations of hereditary hemochromatosis". Retrieved 10 September 2014.CS1 maint: multiple names: authors list (link)
  5. ^ "Hypophosphatasia Pathology". Retrieved 10 September 2014.
  6. ^ Geelhoed, GW; Kelly, TR (December 1989). "Pseudogout as a clue and complication in primary hyperparathyroidism". Surgery. 106 (6): 1036–42. PMID 2588110.

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