Cunninghamella

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Cunninghamella
Cunninghamella echinulata01.jpg
Cunninghamella echinulata
Scientific classification
Kingdom: Fungi
Order: Mucorales
Family: Cunninghamellaceae
Genus: Cunninghamella
Matr. (1903)
Type species
Cunninghamella africana
Matr. 1903
Synonyms[1]
  • Actinocephalum Saito (1905)
  • Muratella Bainier & Sartory (1913)
  • Saitomyces Ricker (1906)

Cunninghamella is a genus of fungi in the order Mucorales, and the family Cunninghamellaceae.[2] The genus was circumscribed by French mycologist Alphonse Louis Paul Matruchot in 1903.[3]

Species[edit]

As of 2015, Index Fungorum lists 13 valid species of Cunninghamella:[4]

Uses[edit]

Members of this genus are often used in studies investigating the metabolism of drugs, because these species metabolize a wide range of drugs in manners similar to mammalian enzyme systems.[5] Many species are also capable of oxidizing polycyclic aromatic hydrocarbons, a class of stable organic molecules that tends to persist in the environment and contains many known carcinogenic and mutagenic compounds.[6]

The presence of a cytochrome P-450 has been demonstrated in C. bainieri.[7]

See also[edit]

References[edit]

  1. ^ "Synonymy: Cunninghamella Matr.". Species Fungorum. CAB International. Retrieved 2015-09-21. 
  2. ^ Cunninghamella at the US National Library of Medicine Medical Subject Headings (MeSH)
  3. ^ Matruchot L. (1903). "Une Mucorinée purement conidienne. Cunninghamella africana". Annales Mycologici (in French) 1: 45–60. 
  4. ^ "Species Fungorum (version 26th August 2015). In: Species 2000 & ITIS Catalogue of Life". Retrieved 2015-09-21. 
  5. ^ Asha S, Vidyavathi M (2009). "Cunninghamella--a microbial model for drug metabolism studies--a review". Biotechnol. Adv. 27 (1): 16–29. doi:10.1016/j.biotechadv.2008.07.005. PMID 18775773. Retrieved 2009-03-17. 
  6. ^ Cerniglia, Carl E. (1992). "Biodegradation of polycyclic aromatic hydrocarbons". Biodegradation 3 (2–3): 351–368. doi:10.1007/BF00129093. 
  7. ^ Aryl hydrocarbon hydroxylase activity in the fungus Cunninghamella bainieri: Evidence for the presence of cytochrome P-450. J.P. Ferris, L.H. MacDonald, M.A. Patrie and M.A. Martin, Archives of Biochemistry and Biophysics, Volume 175, Issue 2, August 1976, pages 443-452, doi:10.1016/0003-9861(76)90532-4

External links[edit]