Cyclomaltodextrin glucanotransferase

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cyclomaltodextrin glucanotransferase
EC number2.4.1.19
CAS number9030-09-5
IntEnzIntEnz view
ExPASyNiceZyme view
MetaCycmetabolic pathway
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a cyclomaltodextrin glucanotransferase (EC is an enzyme that catalyzes the chemical reaction of cyclizing part of a 1,4-alpha-D-glucan molecule through the formation of a 1,4-alpha-D-glucosidic bond.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing). Other names in common use include Bacillus macerans amylase, cyclodextrin glucanotransferase, alpha-cyclodextrin glucanotransferase, alpha-cyclodextrin glycosyltransferase, beta-cyclodextrin glucanotransferase, beta-cyclodextrin glycosyltransferase, gamma-cyclodextrin glycosyltransferase, cyclodextrin glycosyltransferase, cyclomaltodextrin glucotransferase, cyclomaltodextrin glycosyltransferase, konchizaimu, alpha-1,4-glucan 4-glycosyltransferase, cyclizing, BMA, CGTase, and neutral-cyclodextrin glycosyltransferase.

Structural studies[edit]

As of late 2007, 47 structures have been solved for this class of enzymes, with PDB accession codes 1A47, 1CDG, 1CGT, 1CGU, 1CGV, 1CGW, 1CGX, 1CGY, 1CIU, 1CXE, 1CXF, 1CXH, 1CXI, 1CXK, 1CXL, 1CYG, 1D3C, 1D7F, 1DED, 1DTU, 1EO5, 1EO7, 1I75, 1KCK, 1KCL, 1OT1, 1OT2, 1PAM, 1PEZ, 1PJ9, 1TCM, 1UKQ, 1UKS, 1UKT, 1V3J, 1V3K, 1V3L, 1V3M, 2CXG, 2DIJ, 3CGT, 4CGT, 5CGT, 6CGT, 7CGT, 8CGT, and 9CGT.


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