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Tapeworms of the order Cyclophyllidea (the cyclophyllid cestodes) are the most important cestode parasites of humans and domesticated animals. All have multiple proglottid "segments", and all have four suckers on their scolices (heads), though some may have other structures, as well. Proglottids of this order have genital openings on one side (except in the Dilepididae, which have genital openings on both sides), and a compact yolk gland or vitellarium posterior to the ovary.
- Dipylidiidae (formerly Dilepididae), the most important member of which is Dipylidium caninum, also called the "cucumber tapeworm" or the "double-pore tapeworm"
- Hymenolepididae, with the most important genus being Hymenolepis
- Taeniidae, which consists of livestock parasites in the genus Taenia and parasites that encyst in humans of the genus Echinococcus
- Anoplocephalidae, which include several tapeworms of horses and a genus of tapeworms of ruminants, the Moniezia
- Davaineidae that comprise 14 genera, most of which are parasites of birds
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