Cyclopyrrolones

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Skeletal formula of the parent compound, cyclopyrrolone

Cyclopyrrolones are a family of hypnotic and anxiolytic nonbenzodiazepine drugs with similar pharmacological profiles to the benzodiazepine derivatives.

Although cyclopyrrolones are chemically unrelated to benzodiazepines, they function via the benzodiazepine receptor/GABA neurotransmitter. The best-known cyclopyrrolone derivatives are zopiclone (Imovane) and its active single-enantiomer component, eszopiclone (Lunesta), which are used to treat insomnia, and have a known potential for abuse. Other cyclopyrrolones include:

External links[edit]