Cycrimine

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Cycrimine
Cycrimine.svg
Systematic (IUPAC) name
1-Cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol
Clinical data
License data
Identifiers
CAS Number 77-39-4
ATC code none
PubChem CID 2911
DrugBank DB00942
ChemSpider 2808
UNII 543567RFQQ YesY
ChEBI CHEBI:59692 YesY
ChEMBL CHEMBL1201227
Chemical data
Formula C19H29NO
Molar mass 287.4 g/mol

Cycrimine (trade name Pagitane) is a central anticholinergic drug designed to reduce the levels of acetylcholine in the treatment of Parkinson's disease. Its mechanism of action is to bind to the muscarinic acetylcholine receptor M1.[1]

Synthesis[edit]

Cycrimine synthesis:[2]

See also[edit]

References[edit]

  1. ^ Psychotropic Drugs and Related Compounds, 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972, page 218
  2. ^ Denton, J. J.; Schedl, H. P.; Lawson, Virginia A.; Neier, W. B. (1950). "Antispasmodics. VII.1 Additional Morpholinyl and Piperidyl Tertiary Alcohols". Journal of the American Chemical Society 72 (8): 3795–3796. doi:10.1021/ja01164a127. 

External links[edit]