Harris was born in New York City, New York, the daughter of Saul Harris, a businessman. She has appeared in many television series and TV movies, such as Archie Bunker's Place, All My Children, and in the classic drama, Edward and Mrs. Simpson as the Duchess of Windsor. For almost two decades, she played "Mrs. B." in television advertisements for the now-defunct department store chain Bradlees. Harris is perhaps best recognized to television viewers for her guest roles on Three's Company, L.A. Law (1986), the TV adaptation of the Broadway play Edward & Mrs. Simpson (1978), Mad About You (1992). She made her Broadway debut in 1963. In 1971, she appeared on Broadway in the Landmark Stephen Sondheim-George Furth musical, "Company". She is a founding member and co-artistic director of The Actor's Company Theatre. In 1978, she received a BAFTA nomination for her performance as "Wallis Simpson" in Edward & Mrs. Simpson (1978).