Cystathionine

Cystathionine

Names
IUPAC name 2-amino-4-(2-amino-2-carboxy-ethyl) thio-butanoic acid
Other names L-Cystathionine; S-[(2R)-2-Amino-2-carboxyethyl]-L-homocysteine
Identifiers
CAS Number	56-88-2 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:17755 Y
ChEMBL	ChEMBL209241 Y
ChemSpider	388392 N
ECHA InfoCard	100.000.269
KEGG	C00542 Y
MeSH	Cystathionine
PubChem CID	439258
CompTox Dashboard (EPA)	DTXSID20971384
InChI InChI=1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1 N Key: ILRYLPWNYFXEMH-WHFBIAKZSA-N N InChI=1/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13) Key: ILRYLPWNYFXEMH-UHFFFAOYAH
SMILES C(CSC[C@@H](C(=O)O)N)[C@@H](C(=O)O)N
Properties
Chemical formula	C7H14N2O4S
Molar mass	222.26 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Cystathionine is an intermediate in the synthesis of cysteine.

An excess in the urine is called cystathioninuria.

Biosynthetically, cystathionineis generated from homocysteine and serine by cystathionine beta synthase (upper reaction in the diagram below). It is then cleaved into cysteine and α-ketobutyrate by cystathionine gamma-lyase (lower reaction).

Cysteine metabolism. Cystathionine beta synthase catalyzes the upper reaction and cystathionine gamma-lyase catalyzes the lower reaction.