Cysteinyl leukotriene receptor 2

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Aliases CYSLTR2, CYSLT2, CYSLT2R, HG57, HPN321, KPG_011, hGPCR21, GPCR21, PSEC0146, cysteinyl leukotriene receptor 2
External IDs MGI: 1917336 HomoloGene: 10688 GeneCards: 57105
RNA expression pattern
PBB GE CYSLTR2 220813 at tn.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)


RefSeq (protein)


Location (UCSC) Chr 13: 48.65 – 48.71 Mb Chr 14: 73.03 – 73.05 Mb
PubMed search [1] [2]
View/Edit Human View/Edit Mouse

Cysteinyl leukotriene receptor 2 is a protein that in humans is encoded by the CYSLTR2 gene.[3][4][5]

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1.[citation needed] This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems.[5]

See also[edit]


  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Takasaki J, Kamohara M, Matsumoto M, Saito T, Sugimoto T, Ohishi T, Ishii H, Ota T, Nishikawa T, Kawai Y, Masuho Y, Isogai T, Suzuki Y, Sugano S, Furuichi K (Aug 2000). "The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor". Biochem Biophys Res Commun. 274 (2): 316–22. doi:10.1006/bbrc.2000.3140. PMID 10913337. 
  4. ^ Van Keer C, Kersters K, De Ley J (Sep 1976). "L-Sorbose metabolism in Agrobacterium tumefaciens". Antonie Van Leeuwenhoek. 42 (1–2): 13–24. doi:10.1007/BF00399445. PMID 1085123. 
  5. ^ a b "Entrez Gene: CYSLTR2 cysteinyl leukotriene receptor 2". 

External links[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.