D. George Wyse

From Wikipedia, the free encyclopedia
Jump to: navigation, search

D. George Wyse FRCPC is the Chair of the International Experts Advisory Committee of the Libin Cardiovascular Institute of Alberta (LCIA).[1] Wyse is a recognized and decorated international expert in the area of cardiac arrhythmias. His research led to fundamental changes in the way cardiac arrhythmias are treated, in specific, the reduction in use of certain antiarrhythmic agents.


Wyse obtained his PhD in Pharmacology in 1969 from McGill University in Montreal, Quebec, Canada and subsequently conducted two years of postdoctoral research at the University of New Mexico in Albuquerque, New Mexico. After his stint in the United States, Wyse returned to Canada, completing his MD training in 1974 at the University of Calgary.[2] By 1978, Wyse had completed specialization training in internal medicine at the Foothills Medical Centre, also located in Calgary, followed by training in cardiology at Oregon Health Sciences University in Portland, Oregon.



Within the area of cardiac arrhythmia and antiarrhythmic agents, Wyse has played an integral role in some of the more defining trials over the last three decades. These trials include the Cardiac Arrhythmia Suppression Trial (CAST), the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial and the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) trial. As a result of these trials and other research, Wyse has produced over 300 articles in his active research career. His legacy includes being a founding coordinator of the Medical Research Council of Canada’s Program Grant in cardiac electrophysiology at the University of Calgary.[3][4][5][6]

Honors and awards[edit]


  1. ^ International Experts Advisory Committee - Libin Cardiovascular Institute of Alberta
  2. ^ Press Release - Lecture to Seniors
  3. ^ May 12, 2007 edition of Heart Rhythm Daily - a publication of the Heart Rhythm Society
  4. ^ Wyse D, Waldo A, DiMarco J, Domanski M, Rosenberg Y, Schron E, Kellen J, Greene H, Mickel M, Dalquist J, Corley S (2002). "A comparison of rate control and rhythm control in patients with atrial fibrillation". N Engl J Med. 347 (23): 1825–33. PMID 12466506. doi:10.1056/NEJMoa021328. 
  5. ^ Wyse DG, Morganroth J, Ledingham R, Denes P, Hallstrom A, Mitchell LB, Epstein AE, Woosley RL, Capone R (1994). "New insights into the definition and meaning of proarrhythmia during initiation of antiarrhythmic drug therapy from the Cardiac Arrhythmia Suppression Trial and its pilot study. The CAST and CAPS Investigators". J Am Coll Cardiol. 23 (5): 1130–40. PMID 8144779. doi:10.1016/0735-1097(94)90601-7. 
  6. ^ "Dr. D. George Wyse - antiarrhythmic drugs". Archived from the original on August 23, 2007. Retrieved 2008-08-27. 
  7. ^ Citation - Distinguished Alumni
  8. ^ Distinguished Scientist - Heart Rhythm Society
  9. ^ Citation - Top 40 Alumni
  10. ^ Citation - CCS Annual Achievement Award
  11. ^ https://ucalgary.ca/utoday/issue/2017-02-22/george-wyse-speak-2017-lecture-lifetime

External links[edit]