DDX6

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DDX6
Protein DDX6 PDB 1vec.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases DDX6, HLR2, P54, RCK, DEAD-box helicase 6
External IDs MGI: 104976 HomoloGene: 3238 GeneCards: DDX6
RNA expression pattern
PBB GE DDX6 204909 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001257191
NM_004397

NM_001110826
NM_007841
NM_181324

RefSeq (protein)

NP_001244120
NP_004388

Location (UCSC) Chr 11: 118.75 – 118.79 Mb Chr 9: 44.6 – 44.64 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Probable ATP-dependent RNA helicase DDX6 is an enzyme that in humans is encoded by the DDX6 gene.[3][4]

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein. It may contribute to the cell proliferation and carcinogenesis.[4]

References[edit]

Further reading[edit]