DEGS2

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DEGS2
Identifiers
Aliases DEGS2, C14orf66, DES2, FADS8, delta(4)-desaturase, sphingolipid 2, delta 4-desaturase, sphingolipid 2
External IDs MGI: 1917309 HomoloGene: 23617 GeneCards: DEGS2
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_206918

NM_001171002
NM_027299

RefSeq (protein)

NP_996801

NP_001164473.1
NP_081575.2
NP_001164473
NP_081575

Location (UCSC) Chr 14: 100.14 – 100.16 Mb Chr 12: 108.69 – 108.7 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Delta(4)-desaturase, sphingolipid 2 is a protein that in humans is encoded by the DEGS2 gene.[3]

Function[edit]

This gene encodes a bifunctional enzyme that is involved in the biosynthesis of sphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase.

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.